NovoPro
Cart 2
  • SARS-CoV-2 NSP8 (E.coli, C-6His)

SARS-CoV-2 NSP8 (E.coli, C-6His)

Cat.#: 521016

Size:

Special Price 369.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    SARS-CoV-2 NSP8 (E.coli, C-6His)
  • Documents
  • Description
    Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
  • Uniprot ID
    YP_009725304.1
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    The target gene encoding NSP8(YP_009725304.1) Ala1-Gln198 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    2019-nCoV
  • Molecular weight
    25kDa, reducing conditions.
  • Purity
    >90%
  • Validations

    SARS-CoV-2 NSP8 (E.coli, C-6His)

    SARS-CoV-2 NSP8 (E.coli, C-6His)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"