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  • Rat Kitlg/Kitl/Mgf (His tag) recombinant protein

Rat Kitlg/Kitl/Mgf (His tag) recombinant protein

Cat.#: 519877

Special Price 261.2 USD

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Product Information

  • Product Name
    Rat Kitlg/Kitl/Mgf (His tag) recombinant protein
  • Documents
  • Description
    Stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.
  • Protein name
    KIT ligand(Kitlg)
  • Protein short names
    Kitl; Mgf
  • Uniprot ID
    P21581
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Rat Kitlg/Kitl/Mgf Gln26-Ala189 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Rat
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Rat Kitlg/Kitl/Mgf (His tag) recombinant protein

    Rat Kitlg/Kitl/Mgf (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"