Rat FASLG recombinant protein (N-His)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Fas ligand; TNF superfamily, member 6; Tumor necrosis factor ligand 1a
A DNA sequence encoding the rat FASLG (NP_037040.1) (Leu104-Leu278) was expressed with a polyhistidine tag at the N-terminus.
The recombinant rat FASLG consists of 185 amino acids and predicts a molecular mass of 21.3 kDa.
> 95 % as determined by SDS-PAGE.
Rat Fas Ligand / FASLG / CD95L Protein 15468
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