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  • Rat Cd86/rCG_52586 (His tag) recombinant protein

Rat Cd86/rCG_52586 (His tag) recombinant protein

Cat.#: 519009

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Product Information

  • Product Name
    Rat Cd86/rCG_52586 (His tag) recombinant protein
  • Documents
  • Description
    T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
  • Protein name
    CD86 molecule(Cd86)
  • Protein short names
    rCG_52586
  • Uniprot ID
    O35531
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Rat Cd86/rCG_52586 Vla29-Lys247 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Rat
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Rat Cd86/rCG_52586 (His tag) recombinant protein

    Rat Cd86/rCG_52586 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"