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  • Rat Cd80/B7.1 (His tag) recombinant protein

Rat Cd80/B7.1 (His tag) recombinant protein

Cat.#: 518321

Special Price 265.0 USD

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Product Information

  • Product Name
    Rat Cd80/B7.1 (His tag) recombinant protein
  • Documents
  • Description
    Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
  • Protein name
    Cd80 molecule(Cd80)
  • Protein short names
    B7.1
  • Uniprot ID
    O35187
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Rat Cd80/B7.1 Vla30-Gln248 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Rat
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Rat Cd80/B7.1 (His tag) recombinant protein

    Rat Cd80/B7.1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"