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Product Name
Rat CD48/SLAMF2 (His Tag) recombinant protein
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Description
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
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Protein name
CD48 antigen
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Protein short names
BLAST; BCM-1; MCD48; MEM-102; AI449234; AW610730; SLAMF2; BLAST-1; SGP-60; CD48; BCM1; HCD48; BLAST1
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Uniprot ID
P10252
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Gene Name
Cd48; Bcm-1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat CD48 (P10252) (Met1-Arg216) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Rat CD48 / SLAMF2 / BCM1 Protein (His Tag) SDS-PAGE
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