Rabbit Anti-BDNF Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
WB, IF, IHC-P
Human, Mouse, Rat
ANON2; BULN2; Brain-derived neurotrophic factor; BDNF; Abrineurin antibody
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
WB: 1:100~1:500, IHC-P: 1:100~1:500
Mouse heart lysates probed with (121014) at 1:300 overnight in 4˚C. Followed by conjugation to the secondary antibody at 1:5000 90min in 37˚C.
Formalin-fixed and paraffin embedded rat brain labeled with Anti-BDNF Polyclonal Antibody, Unconjugated (121014) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
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