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  • Rabbit Anti-BDNF Polyclonal Antibody
  • Rabbit Anti-BDNF Polyclonal Antibody

Rabbit Anti-BDNF Polyclonal Antibody

Cat.#: 121014

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Special Price 372.6 USD

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Product Information

  • Product Name
    Rabbit Anti-BDNF Polyclonal Antibody
  • Documents
  • Description
    Purified Rabbit Polyclonal Antibody (Pab)
  • Tested applications
    WB, IF, IHC-P
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    ANON2; BULN2; Brain-derived neurotrophic factor; BDNF; Abrineurin antibody
  • Isotype
    Rabbit IgG
  • Clonality
    Polyclonal
  • Formulation
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
  • Storage instructions
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
  • Applications
    WB: 1:100~1:500, IHC-P: 1:100~1:500
  • Validations

    Mouse heart lysates probed with (121014) at 1:300 overnight in 4˚C. Followed by conjugation to the secondary antibody at 1:5000 90min in 37˚C.

    Mouse heart lysates probed with (121014) at 1:300 overnight in 4˚C. Followed by conjugation to the secondary antibody at 1:5000 90min in 37˚C.

    Formalin-fixed and paraffin embedded rat brain labeled with Anti-BDNF Polyclonal Antibody, Unconjugated (121014) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

    Formalin-fixed and paraffin embedded rat brain labeled with Anti-BDNF Polyclonal Antibody, Unconjugated (121014) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

  • Background
    During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"