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Human B7-DC/PD-L2/CD273 (Fc Tag) recombinant protein

Cat.#: 500765

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Product Information

  • Product Name
    Human B7-DC/PD-L2/CD273 (Fc Tag) recombinant protein
  • Documents
  • Description
    Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
  • Protein name
    Programmed cell death 1 ligand 2
  • Protein short names
    BA574F11.2; BTDC; B7DC; B7-DC; MGC124039; PD-L2; PDCD1LG2; MGC124040; PDL2; MGC142240; CD273; PDCD1L2; F730015O22RIK; MGC142238
  • Uniprot ID
    Q9BQ51
  • Gene Name
    PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PDCD1LG2 (NP_079515.2) (Met1-Pro219) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human PDCD1LG2 consists 438 amino acids and predicts a molecular mass of 49.3 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human PD1-His (Cat:503606) at 10 μg/mL (100 μL/well) can bind human PDCD1LG2-Fc. The EC50 of PDCD1LG2-Fc is 0.05-0.12 μg/mL.
  • Validations

    Human B7-DC / PD-L2 / CD273 / PDCD1LG2 Protein (Fc Tag) SDS-PAGE

    Human B7-DC / PD-L2 / CD273 / PDCD1LG2 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"