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Mouse B7-DC/PD-L2/CD273 (His Tag) recombinant protein

Cat.#: 500276

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Product Information

  • Product Name
    Mouse B7-DC/PD-L2/CD273 (His Tag) recombinant protein
  • Documents
  • Description
    Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
  • Protein name
    Programmed cell death 1 ligand 2
  • Protein short names
    PDCD1LG2; PD-L2; MGC142238; PDCD1L2; CD273; F730015O22RIK; MGC124040; PDL2; MGC142240; B7DC; BTDC; BA574F11.2; B7-DC; MGC124039
  • Uniprot ID
    Q9WUL5
  • Gene Name
    Pdcd1lg2; B7dc; Btdc; Cd273; Pdl2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of mouse PDCD1LG2 (Q9WUL5) (Met 1-Arg 219) was expressed, with a C-terminal polyhistidine tag.
  • Protein Species
    Mouse
  • Molecular weight
    The secreted recombinant mouse PDCD1LG2 comprises 211 amino acids and has a calculated molecular mass of 24 kDa. As a result of glycosylation, the apparent molecular mass of rmPDCD1LG2 is approximately 35-45 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized mouse PD-L2-his at 10 μg/mL (100 μl/well) can bind mouse PD1-Fc. The EC50 of mouse PD1-Fc is 1.63 μg/mL.
  • Validations

    Mouse B7-DC / PD-L2 / CD273 Protein (His Tag) SDS-PAGE

    Mouse B7-DC / PD-L2 / CD273 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"