Cart 2
  • Human PPARG (His & GST Tag) recombinant protein

Human PPARG (His & GST Tag) recombinant protein

Cat.#: 501331

Size:

Special Price 307.5 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human PPARG (His & GST Tag) recombinant protein
  • Documents
  • Description
    Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity).
  • Protein name
    Peroxisome proliferator-activated receptor gamma
  • Protein short names
    PPAR-GAMMA; PPARGAMMA; PPARG2; PPARG1; NR1C3; PPAR-GAMMA2; CIMT1; GLM1; PPARGAMMA2
  • Uniprot ID
    P37231
  • Gene Name
    PPARG; NR1C3
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PPARG isoform 2 (P37231-1) (Met 1-Tyr 505) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human PPARG/GST chimera consists of 742 amino acids and has a calculated molecular mass of 85.4 kDa. It migrates as an approximately 85.4 kDa band in SDS-PAGE under reducing conditions as predicted.
  • Purity
    > 65 % as determined by SDS-PAGE
  • Validations

    Human PPARG / Nr1c3 / PPARgamma Protein (His & GST Tag) SDS-PAGE

    Human PPARG / Nr1c3 / PPARgamma Protein (His & GST Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"