Human FKBP7 / Rotamase (His Tag) recombinant protein

Human FKBP7 / Rotamase (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

PPIase is a member of the immunophilin protein family. It also belongs to the cyclophilin-type PPIase family, PPIL3 subfamily. PPIase contains 1 PPIase cyclophilin-type domain. Members of the immunophilin protein family play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It has a very high substrate specificity for the four-residue peptide Ala-Ala-Pro-Phe only when the proline peptide bond is in the trans state. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Peptidyl-prolyl cis-trans isomerase FKBP7

23 KDA FK506-BINDING PROTEIN; FKBP-7; FKBP23; PPIASE FKBP7; PPIASE; FKBP-23; MGC9420; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7; FK506-BINDING PROTEIN 23; FK506-BINDING PROTEIN 7; UNQ670/PRO1304; 23KDA; 23 KDA FKBP; ROTAMASE; RP23-468L22.3

Q9Y680

FKBP7; FKBP23; UNQ670/PRO1304

Human Cells

A DNA sequence encoding the human FKBP7 (Q9Y680-2) (Met1-Gln218) was expressed with a polyhistidine tag at the C-terminus.

Human

The recombinant human FKBP7 consists of 206 amino acids and predicts a molecular mass of 23.8 KDa. It migrates as an approximately 27and 30 KDa band in SDS-PAGE under reducing conditions.

(84.2+12.5) % as determined by SDS-PAGE