Mouse CD33 / Siglec-3 (Fc Tag) recombinant protein

Cat.#: 502792

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Product Information

  • Product Name
    Mouse CD33 / Siglec-3 (Fc Tag) recombinant protein
  • Documents
  • Description
    Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
  • Protein name
    Myeloid cell surface antigen CD33
  • Protein short names
    SIGLEC-3; SIGLEC3; CD33; P67; FLJ00391; GP67
  • Uniprot ID
    Q63994
  • Gene Name
    Cd33; Siglec3
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of mouse CD33 (Q63994-1) (Met 1-Glu 240) was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The secreted recombinant mouse CD33/Fc is a disulfide-linked homodimer. The reduced monomer comprises 465 amino acids and has a calculated molecular mass of 51.6 kDa. As a result of glycosylation, the apparent molecular mass of rm CD33/Fc monomer is approximately 55-60 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Mouse CD33 / Siglec-3 Protein (Fc Tag) SDS-PAGE

    Mouse CD33 / Siglec-3 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"