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MRAP antibody

Cat.#: 112799

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Product Information

  • Product Name
    MRAP antibody
  • Documents
  • Description
    MRAP Rabbit Polyclonal antibody. Positive WB detected in human kidney tissue, HeLa cells, MCF7 cells. Positive IHC detected in human testis tissue, mouse kidney tissue. Observed molecular weight by Western-blot: 12kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    B27 antibody; C21orf61 antibody; FALP antibody; FGD2 antibody; GCCD2 antibody; MRAP antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_178817). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:112799(MRAP antibody) at dilution of 1:300

    human kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:112799(MRAP antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human testis using Catalog No:112799(MRAP antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:112799(MRAP antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:112799(MRAP antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human testis using Catalog No:112799(MRAP antibody) at dilution of 1:50 (under 40x lens)

  • Background
    MRAP, also named as C21orf61, FALP and B27, is required for MC2R expression in certain cell types. MRAP is involved in the processing, trafficking or function of MC2R. MRAP may be involved in the intracellular trafficking pathways in adipocyte cells. Mutation of MRAP will cause glucocorticoid deficiency type 2 (GCCD2) which known as familial glucocorticoid deficiency type 2 (FGD2). The antibody can recognize the isoform1,isoform2 and isoform4.
  • References
    • Evans JF, Rodriguez S, Ragolia L. ACTH promotes chondrogenic nodule formation and induces transient elevations in intracellular calcium in rat bone marrow cell cultures via MC2-R signaling. Cell and tissue research. 352(2):413-25. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"