Mouse Tnfrsf1a/Tnfr-1/Tnfr1 recombinant protein

Mouse Tnfrsf1a/Tnfr-1/Tnfr1 recombinant protein

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• Material Safety Data Sheets (MSDS)

Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome

tumor necrosis factor receptor superfamily, member 1a(Tnfrsf1a)

Tnfr-1; Tnfr1

P25118

E.coli

A DNA sequence encoding the Mouse Tnfrsf1a/Tnfr-1/Tnfr1 Ile22-Ala212 is expressed.

Mouse

>95% as determined by SDS-PAGE.