Mouse Scgb1a1/Cc10/Ugb/Utg (His tag) recombinant protein

Cat.#: 518878

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Product Information

  • Product Name
    Mouse Scgb1a1/Cc10/Ugb/Utg (His tag) recombinant protein
  • Documents
  • Description
    Uteroglobin(UG, SCGB1A1) is the founding member of the secretoglobin family of small,secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is mainly expressed in lung, with anti-inflammatory/immunomodulatory properties. CCAAT/enhancer-binding proteins(C/EBPs) are the major transcription factors for the regulation of SCGB1A1 gene expression, whereas FOXA1 had a minimum effect on the transcription. Uteroglobin is a multifunctional protein with anti-inflammatory/immunomodulatory properties. Uteroglobin inhibits soluble phospholipase A(2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its anti-inflammatory activities, Uteroglobin manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities. Uteroglobin is a potential drug target. The mechanism of Uteroglobin action is likely to be even more complex as it also functions via a putative receptor-mediated pathway.
  • Protein name
    secretoglobin, family 1A, member 1 (uteroglobin)(Scgb1a1)
  • Protein short names
    Cc10; Ugb; Utg
  • Uniprot ID
    Q06318
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Scgb1a1/Cc10/Ugb/Utg Asp22-Phe96 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Scgb1a1/Cc10/Ugb/Utg (His tag) recombinant protein

    Mouse Scgb1a1/Cc10/Ugb/Utg (His tag) recombinant protein

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