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  • Mouse Il13/Il-13 recombinant protein

Mouse Il13/Il-13 recombinant protein

Cat.#: 519534

Special Price 156.8 USD

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Product Information

  • Product Name
    Mouse Il13/Il-13 recombinant protein
  • Documents
  • Description
    Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13Rα2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.
  • Protein name
    interleukin 13(Il13)
  • Protein short names
    Il-13
  • Uniprot ID
    P20109
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Il13/Il-13 Ser26-Phe131 is expressed.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Il13/Il-13 recombinant protein

    Mouse Il13/Il-13 recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"