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  • Mouse Fzd2/Fzd10 (Fc tag) recombinant protein

Mouse Fzd2/Fzd10 (Fc tag) recombinant protein

Cat.#: 519132

Special Price 190.9 USD

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Product Information

  • Product Name
    Mouse Fzd2/Fzd10 (Fc tag) recombinant protein
  • Documents
  • Description
    Wnt signaling plays a critical role in embryonic development, and genetic aberrations. Frizzled2 (Fzd2) is a receptor for wingless-type MMTV integration site family members (Wnts), the aberrant overexpression of which has been noted to contribute to cancer metastasis. Frizzled2 (Fzd2) and its ligands Wnt5a/b are elevated in metastatic liver, lung, colon, and breast cancer cell lines and in high-grade tumors and that their expression correlates with markers of epithelial-mesenchymal transition (EMT). It is also shown that Frizzled-2 expression is greater in embryonic than adult tissues, with heart, brain, lung, kidney and gut showing the highest levels.
  • Protein name
    frizzled class receptor 2(Fzd2)
  • Protein short names
    Fzd10
  • Uniprot ID
    Q9JIP6
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Fzd2/Fzd10 Gln29-Leu168 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Fzd2/Fzd10 (Fc tag) recombinant protein

    Mouse Fzd2/Fzd10 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"