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Product Name
Mouse Fcgr2/Fcgr2b/Ly-17 (His tag) recombinant protein
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Description
Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.
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Protein name
Fc receptor, IgG, low affinity IIb(Fcgr2b)
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Protein short names
Fcgr2b; Ly-17
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Uniprot ID
P08101
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Fcgr2/Fcgr2b/Ly-17 Thr30-Pro210 is expressed with a 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Fcgr2/Fcgr2b/Ly-17 (His tag) recombinant protein
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