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  • Mouse CD47 recombinant protein (C-His)
  • Mouse CD47 recombinant protein (C-His)

Mouse CD47 recombinant protein (C-His)

Cat.#: 514786

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Product Information

  • Product Name
    Mouse CD47 recombinant protein (C-His)
  • Documents
  • Description
    CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.Immune Checkpoint
    Immune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: WB Antibodies
    Immune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
  • Protein short names
    9130415E20Rik,AA407862,AI848868,AW108519,B430305P08Rik,IAP,Itgp
  • Uniprot ID
    ADQ12919.1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse CD47 (ADQ12919.1) (Met1-Lys140) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse CD47 consists of 133 amino acids and predicts a molecular mass of 15.3 kDa.
  • Purity
    > 90 % as determined by SDS-PAGE.
  • Activity
    Measured by its ability to bind mouse SIRPA-Fc (Cat:50956-M02H)in functional ELISA.
  • Validations

    Mouse CD47 Protein 15526

    Mouse CD47 Protein 15526

    Mouse CD47 Protein (His Tag)

    Mouse CD47 Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"