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Product Name
Mouse MIF recombinant protein
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Description
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity).
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Protein name
Macrophage migration inhibitory factor
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Protein short names
GLIF; DER6; MIF; MGC107654; GIF; MMIF
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Uniprot ID
P34884
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Gene Name
Mif
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse MIF (P34884) precursor (Pro 2-Ala 115) was expressed, with an initial Met at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse MIF consists of 115 amino acids and has a calculated molecular mass of 12.5 kDa. It migrates as an approximately 13 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 93 % as determined by SDS-PAGE
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Validations
Mouse MIF / Migration Inhibitory Factor Protein SDS-PAGE
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