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  • Rat CD47 (His Tag) recombinant protein

Rat CD47 (His Tag) recombinant protein

Cat.#: 500893

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Product Information

  • Product Name
    Rat CD47 (His Tag) recombinant protein
  • Documents
  • Description
    Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection (By similarity). Plays an important role in memory formation and synaptic plasticity in the hippocampus.
  • Protein name
    Leukocyte surface antigen CD47
  • Protein short names
    ITGP; AW108519; CD47 ANTIGEN (RH-RELATED ANTIGEN; ANTIGEN IDENTIFIED BY MONOCLONAL ANTIBODY 1D8; AI848868; LEUKOCYTE SURFACE ANTIGEN CD47; IAP; INTEGRIN ASSOCIATED PROTEIN; RH-RELATED ANTIGEN; B430305P08RIK; OA3; INTEGRIN-ASSOCIATED PROTEIN; MER6; INTEGRIN-ASSOCIATED SIGNAL TRANSDUCER); CD47 GLYCOPROTEIN; 9130415E20RIK; INTEGRIN-ASSOCIATED SIGNAL TRANSDUCER; ANTIGENIC SURFACE DETERMINANT PROTEIN OA3; AA407862
  • Uniprot ID
    P97829
  • Gene Name
    Cd47
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat CD47 (P97829-1) (Met1-Lys140) was expressed, fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat CD47 comprises 133 amino acids and predicts a molecular mass of 15.2 kDa. The apparent molecular mass of the recombinant protein is approximately 27-35 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized Rat CD47-His at 10 μg/ml (100 μl/well) can bind mouse SIRPA-Fc (Cat:503641), The EC50 of mouse SIRPA-Fc (Cat:503641) is 0.6-1.4 μg/ml.
  • Validations

    Rat CD47 Protein (His Tag) SDS-PAGE

    Rat CD47 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"