Human KLK11/Kallikrein 11 (His Tag) recombinant protein

Cat.#: 500636

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Product Information

  • Product Name
    Human KLK11/Kallikrein 11 (His Tag) recombinant protein
  • Documents
  • Description
    Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.
  • Protein name
    Kallikrein-11
  • Protein short names
    MGC33060; MGC144345; KALLIKREIN 11; 2310015I08RIK; PRSS20; KLK11; TLSP
  • Uniprot ID
    Q9UBX7
  • Gene Name
    KLK11; PRSS20; TLSP; UNQ649/PRO1279
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human KLK11 isoform 1 (NP_006844.1) (Met 1-Asn 250) with a C-terminal polyhistidine tag was expressed.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human KLKL11 comprises 243 amino acids with a predicted molecular mass of 27 kDa. As a result of glycosylation, rhKLK11 migrates as an approximately 40 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to cleave a colorimetric peptide substrate D-Val-Leu-Lys-ThioBenzyl ester (VLK-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB) (Edwards, K.M. et al.,1999, J. Biol. Chem. 274: 30468). The specific activity is >200 pmoles/min/μg.
  • Validations

    Human KLK11 / Kallikrein-11 Protein (His Tag) SDS-PAGE

    Human KLK11 / Kallikrein-11 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"