Human MMP-1/MMP1 (His Tag) recombinant protein

Cat.#: 500009

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Product Information

  • Product Name
    Human MMP-1/MMP1 (His Tag) recombinant protein
  • Documents
  • Description
    Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
  • Protein name
    Interstitial collagenase
  • Protein short names
    CLGN; MMP13]; MMP-13; MMP1; CLG
  • Uniprot ID
    Q53G95
  • Gene Name
    MMP1; CLG
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the pro form of human MMP1 enzyme (NP_002412.1) precursor (Met 1-Asn 469) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human MMP1 comprises 461 amino acids migrates as an approximately 50-55 kDa band as estimated in SDS-PAGE under reducing conditions.
  • Purity
    > 96 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2, R&D System, Cat#ES010. The specific activity is >70 pmoles/min/μg.
  • Validations

    Human MMP1 Protein (His Tag) SDS-PAGE

    Human MMP1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"