Rat IL7 / interleukin-7 recombinant protein

Cat.#: 502444

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Product Information

  • Product Name
    Rat IL7 / interleukin-7 recombinant protein
  • Documents
  • Description
    IL7, also known as interleukin 7, is a hematopoietic growth factor which belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.
  • Protein name
    Interleukin-7
  • Protein short names
    HLB368; INTERLEUKIN 7; IL7; A630026I06RIK; IL-7
  • Uniprot ID
    Q91Y32
  • Gene Name
    Il7; IL-7
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat IL7 (Q91Y32) (Asp26-Ile154) was expressed and purified with an initial Met.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat IL7 consists of 130 amino acids and has a predicted molecular mass of 15 kDa. The apparent molecular mass of the recombinant protein is approximately 17 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to bind rat IL7R-mFc (Cat:501881) in a functional ELISA.
  • Validations

    Rat IL7 / interleukin 7 Protein SDS-PAGE

    Rat IL7 / interleukin 7 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"