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Product Name
Human IL12B/IL-12B (Fc Tag) recombinant protein
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Description
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
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Protein name
Interleukin-12 subunit beta
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Protein short names
IL12P40; RP23-388G23.1; IMD29; NKSF2; IL-12B; IL-12P40; IMD28; IL12B; NKSF; CLMF; CLMF2; P40
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Uniprot ID
P29460
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Gene Name
IL12B; NKSF2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the p40 subunit of human IL12, termed asIL12B (NP_002178.2) (Met 1-Ser 328) was fused with the Fc region ofhuman IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human IL12B consists of 544 amino acids and has a predicted molecular mass of 61.4 kDa.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized human IL12RB1 at 20 μg/ml (100 μl/well) can bind human IL12B with a linear ranger of 2.56-64 ng/ml. -
Validations
Human IL12B / P40 Protein (Fc Tag) SDS-PAGE
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