Human TNFRSF11A/RANK (His tag) recombinant protein

Human TNFRSF11A/RANK (His tag) recombinant protein

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• Material Safety Data Sheets (MSDS)

Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.

TNF receptor superfamily member 11a(TNFRSF11A)

RANK

Q9Y6Q6

Human Cells

A DNA sequence encoding the Human TNFRSF11A/RANK Ile30-Pro212 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.