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Product Name
Human SRPK2 (His tag) recombinant protein
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Description
SRSF Protein Kinase 2 (SRPK2) belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Serine/arginine-rich protein-specific kinase that specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. SFRSK2 can be cleaved into SRSF protein kinase 2 N-terminal and SRSF protein kinase 2 C-terminal chains and contains one protein kinase domain. SFRSK2 can mediate hepatitis B virus (HBV) core protein phosphorylation. SFRSK2 plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein.
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Protein name
SRSF protein kinase 2(SRPK2)
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Uniprot ID
P78362
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SRPK2 Met1-Ser688 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SRPK2 (His tag) recombinant protein
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