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  • Human SCARB2/CD36L2/LIMP2/LIMPII (His tag) recombinant protein

Human SCARB2/CD36L2/LIMP2/LIMPII (His tag) recombinant protein

Cat.#: 519796

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Product Information

  • Product Name
    Human SCARB2/CD36L2/LIMP2/LIMPII (His tag) recombinant protein
  • Documents
  • Description
    Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.
  • Protein name
    scavenger receptor class B member 2(SCARB2)
  • Protein short names
    CD36L2; LIMP2; LIMPII
  • Uniprot ID
    Q14108
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human SCARB2/CD36L2/LIMP2/LIMPII Arg27-Thr432 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human SCARB2/CD36L2/LIMP2/LIMPII (His tag) recombinant protein

    Human SCARB2/CD36L2/LIMP2/LIMPII (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"