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  • Human RPS6KA1/MAPKAPK1A/RSK1 (His tag) recombinant protein

Human RPS6KA1/MAPKAPK1A/RSK1 (His tag) recombinant protein

Cat.#: 518606

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Product Information

  • Product Name
    Human RPS6KA1/MAPKAPK1A/RSK1 (His tag) recombinant protein
  • Documents
  • Description
    Ribosomal protein S6 kinase alpha-1(RPS6KA1) contains 1 AGC-kinase C-terminal domain, contains 2 protein kinase domains and belongs to the protein kinase superfamily. In fibroblast, RPS6KA1 is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA),It phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP. Upon insulin-derived signal,it acts indirectly on the transcription regulation of several genes by phosphorylating GSK3B at 'Ser-9' and inhibiting its activity.
  • Protein name
    ribosomal protein S6 kinase A1(RPS6KA1)
  • Protein short names
    MAPKAPK1A; RSK1
  • Uniprot ID
    Q15418
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human RPS6KA1/MAPKAPK1A/RSK1 Met1-Leu735 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human RPS6KA1/MAPKAPK1A/RSK1 (His tag) recombinant protein

    Human RPS6KA1/MAPKAPK1A/RSK1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"