Human RETN/FIZZ3/HXCP1/RSTN (His tag) recombinant protein

Cat.#: 519915

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Product Information

  • Product Name
    Human RETN/FIZZ3/HXCP1/RSTN (His tag) recombinant protein
  • Documents
  • Description
    Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.
  • Protein name
    resistin(RETN)
  • Protein short names
    FIZZ3; HXCP1; RSTN; UNQ407; PRO1199
  • Uniprot ID
    Q9HD89
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human RETN/FIZZ3/HXCP1/RSTN Lys19-Pro108 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human RETN/FIZZ3/HXCP1/RSTN (His tag) recombinant protein

    Human RETN/FIZZ3/HXCP1/RSTN (His tag) recombinant protein

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