Human PPBP/CTAP3/CXCL7/SCYB7/TGB1/THBGB1 (His tag) recombinant protein

Cat.#: 519818

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Product Information

  • Product Name
    Human PPBP/CTAP3/CXCL7/SCYB7/TGB1/THBGB1 (His tag) recombinant protein
  • Documents
  • Description
    Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and βthrombogulin (βTG), are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, βTG, and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.
  • Protein name
    pro-platelet basic protein(PPBP)
  • Protein short names
    CTAP3; CXCL7; SCYB7; TGB1; THBGB1
  • Uniprot ID
    P02775
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PPBP/CTAP3/CXCL7/SCYB7/TGB1/THBGB1 Ser35-Asp128 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PPBP/CTAP3/CXCL7/SCYB7/TGB1/THBGB1 (His tag) recombinant protein

    Human PPBP/CTAP3/CXCL7/SCYB7/TGB1/THBGB1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"