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  • Human MAPT/MAPTL/MTBT1/TAU (His tag) recombinant protein

Human MAPT/MAPTL/MTBT1/TAU (His tag) recombinant protein

Cat.#: 518292

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Product Information

  • Product Name
    Human MAPT/MAPTL/MTBT1/TAU (His tag) recombinant protein
  • Documents
  • Description
    Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective, and no longer stabilize microtubules properly, it can result in dementias such as Alzheimer's disease and other tauopathies.
  • Protein name
    microtubule associated protein tau(MAPT)
  • Protein short names
    MAPTL; MTBT1; TAU
  • Uniprot ID
    P10636
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human MAPT/MAPTL/MTBT1/TAU Gln249-Gln381 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human MAPT/MAPTL/MTBT1/TAU (His tag) recombinant protein

    Human MAPT/MAPTL/MTBT1/TAU (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"