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  • Human LIF Recombinant protein (GST tag)

Human LIF Recombinant protein (GST tag)

Cat.#: 509517

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human LIF Recombinant protein (GST tag)
  • Documents
  • Description
    Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It’s involved in growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. LIF has potent proinflammatory property, being the inducer of the acute phase protein synthesis and affecting the cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that are capable to regulate the differentiation of embryonic stem cells, hematopoietic and neuronal cells. LIF binds to the specific LIF receptor (LIFR-α) which forms a heterodimer with a specific subunit common to all members of that family of receptors, the GP130 signal transducing subunit. This leads to activation of the JAK/STAT and MAPK cascades. Due to its polyfunctional activities, LIF is involved in the pathogenic events and development of many diseases of various origin.
  • Protein name
    Leukemia inhibitory factor
  • Protein short names
    HILDA; MLPLI; RP23-329P17.1; DIA; D FACTOR; OTTMUSP00000005253; CDF
  • Uniprot ID
    P15018
  • Gene Name
    LIF; HILDA
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    27-202 aa encoded by BC093733 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human LIF SDS-PAGE

    Recombinant human LIF SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"