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Product Name
Human LFA-3 / CD58 (His Tag) recombinant protein
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Description
CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.
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Protein name
CD58 protein
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Protein short names
LFA-3; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3; CD58 MOLECULE; LFA3; SURFACE GLYCOPROTEIN LFA-3; CD58; RP5-1086K13.2; CD58 ANTIGEN; AG3
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Uniprot ID
Q9BRW0
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Gene Name
CD58
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD58 (AAH05930.1) (Met1-Arg215) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CD58 consists of 198 amino acids and predicts a molecular mass of 22.9 KDa. It migrates as an approximately 38-43 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human LFA-3 / CD58 Protein (His Tag) SDS-PAGE
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