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  • Human JAG1/JAGL1 (Fc tag) recombinant protein

Human JAG1/JAGL1 (Fc tag) recombinant protein

Cat.#: 519840

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Product Information

  • Product Name
    Human JAG1/JAGL1 (Fc tag) recombinant protein
  • Documents
  • Description
    Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development, JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1, which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations.
  • Protein name
    jagged 1(JAG1)
  • Protein short names
    JAGL1
  • Uniprot ID
    P78504
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human JAG1/JAGL1 Gln34-Ser1046 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human JAG1/JAGL1 (Fc tag) recombinant protein

    Human JAG1/JAGL1 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"