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  • Human IL18/IGIF/IL1F4 (His tag) recombinant protein

Human IL18/IGIF/IL1F4 (His tag) recombinant protein

Cat.#: 519079

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Product Information

  • Product Name
    Human IL18/IGIF/IL1F4 (His tag) recombinant protein
  • Documents
  • Description
    Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.
  • Protein name
    interleukin 18(IL18)
  • Protein short names
    IGIF; IL1F4
  • Uniprot ID
    Q14116
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IL18/IGIF/IL1F4 Tyr37-Asp193 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IL18/IGIF/IL1F4 (His tag) recombinant protein

    Human IL18/IGIF/IL1F4 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"