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  • Human IFNG recombinant protein (Native)

Human IFNG recombinant protein (Native)

Cat.#: 514793

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Product Information

  • Product Name
    Human IFNG recombinant protein (Native)
  • Documents
  • Description
    IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
  • Protein name
    Interferon gamma
  • Protein short names
    IFG,IFI,IFN gamma,Interferon Gamma
  • Uniprot ID
    P01579
  • Gene Name
    Interferon gamma; IFN-gamma; Immune interferon
  • Source/Expression Host
    CHO Stable Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IFNG (NP_000610.2) (Met 1-Gln 166) was expressed and purified.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human IFNG consists of 143 amino acids and has a predicted molecular mass of 16.7 kDa.
  • Purity
    > (59.9+28.9) % as determined by SDS-PAGE
  • Validations

    Human Interferon Gamma/IFN gamma/IFNG Protein 14823

    Human Interferon Gamma/IFN gamma/IFNG Protein 14823

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"