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  • Human ICOS/AILIM (Fc tag) recombinant protein

Human ICOS/AILIM (Fc tag) recombinant protein

Cat.#: 519924

Special Price 265.0 USD

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Product Information

  • Product Name
    Human ICOS/AILIM (Fc tag) recombinant protein
  • Documents
  • Description
    Inducible T-cell costimulator, also known as activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1 and ICOS, belongs to the CD28 and CTLA4 cell surface receptor family.. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin, ICOS plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1, which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antige
  • Protein name
    inducible T-cell costimulator(ICOS)
  • Protein short names
    AILIM
  • Uniprot ID
    Q9Y6W8
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ICOS/AILIM Glu21-Phe141 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ICOS/AILIM (Fc tag) recombinant protein

    Human ICOS/AILIM (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"