Human HBEGF Recombinant protein (His tag)
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Proheparin-binding EGF-like growth factor
Protein short names
HBEGF; MGC107656; DTR; AW047313; DTS; HEGFL; DTSF
HBEGF; DTR; DTS; HEGFL
25-162 aa encoded by BC033097 was inserted into PET28a vector
Recombinant human HBEGF SDS-PAGE
Related Products / Services
- Recombinant Proteins
- cDNA Clones
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