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  • Human HAMP Recombinant protein (GST tag)

Human HAMP Recombinant protein (GST tag)

Cat.#: 508538

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Product Information

  • Product Name
    Human HAMP Recombinant protein (GST tag)
  • Documents
  • Description
    Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005). {PubMed:22306005}.; Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa (PubMed:11113131, PubMed:11034317). {PubMed:11034317, PubMed:11113131}.
  • Protein name
    Hepcidin
  • Protein short names
    HEPC; LEAP1
  • Uniprot ID
    P81172
  • Gene Name
    HAMP; HEPC; LEAP1; UNQ487/PRO1003
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    25-84 aa encoded by NM_021175 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human HAMP SDS-PAGE

    Recombinant human HAMP SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"