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  • Human GAPDH Recombinant protein (GST tag)

Human GAPDH Recombinant protein (GST tag)

Cat.#: 508154

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Product Information

  • Product Name
    Human GAPDH Recombinant protein (GST tag)
  • Documents
  • Description
    Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
  • Protein name
    Glyceraldehyde-3-phosphate dehydrogenase
  • Protein short names
    MGC88685; MGC102544; MGC105239; MGC103191; G3PD; CDABP0047; HEL-S-162EP; GAPD; MGC103190; MGC102546
  • Uniprot ID
    P04406
  • Gene Name
    GAPDH; GAPD; CDABP0047; OK/SW-cl.12
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    1-335 aa encoded by BC004109 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human GAPDH SDS-PAGE

    Recombinant human GAPDH SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"