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Product Name
Human FKBP3/FKBP25 (His tag) recombinant protein
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Description
FKBP3 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
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Protein name
FK506 binding protein 3(FKBP3)
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Protein short names
FKBP25
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Uniprot ID
Q00688
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human FKBP3/FKBP25 Met1-Asp224 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human FKBP3/FKBP25 (His tag) recombinant protein
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