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  • Human FGF1/FGFA recombinant protein

Human FGF1/FGFA recombinant protein

Cat.#: 519252

Special Price 329.2 USD

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Product Information

  • Product Name
    Human FGF1/FGFA recombinant protein
  • Documents
  • Description
    FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.
  • Protein name
    fibroblast growth factor 1(FGF1)
  • Protein short names
    FGFA
  • Uniprot ID
    P05230
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human FGF1/FGFA Ala2-Asp155 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human FGF1/FGFA recombinant protein

    Human FGF1/FGFA recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"