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  • Human FCRL1/FCRH1 (His Tag) recombinant protein

Human FCRL1/FCRH1 (His Tag) recombinant protein

Cat.#: 503203

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Product Information

  • Product Name
    Human FCRL1/FCRH1 (His Tag) recombinant protein
  • Documents
  • Description
    Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.
  • Protein name
    Cystatin-S
  • Protein short names
    A230020G22RIK; BXMH1B; BXMAS1; FCRH1; IRTA5; FCRL1; BXMH1; CD307A; FCRH1S; DKFZP667O1421; FCRH1L; IFGP1
  • Uniprot ID
    P01036
  • Gene Name
    CST4
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human FCRL1 (NP_001890.1) extracellular domain (Met 1-Asn 303) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human FCRL1 consists of 298 amino acids and has a calculated molecular mass of 32.6 kDa. It migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 98 % as determined by SDS-PAGE
  • Validations

    Human FCRL1 / FCRH1 Protein (His Tag) SDS-PAGE

    Human FCRL1 / FCRH1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"