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  • Human Ephrin-B2 recombinant protein

Human Ephrin-B2 recombinant protein

Cat.#: 503264

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Product Information

  • Product Name
    Human Ephrin-B2 recombinant protein
  • Documents
  • Description
    EphrinB2 also known as EFNB2 is a member of the ephrin family. EphrinB2 is involved in establishing arterial versus venous identity and perhaps in anastamosing arterial and venous vessels at their junctions. The transmembrane-associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. EphrinB2 expression progressively extends from the arterial endothelium to surrounding smooth muscle cells and to pericytes, suggesting that ephrin-B2 may play an important role during formation of the arterial muscle wall.
  • Protein name
    Ephrin-B2
  • Protein short names
    HTKL; EFNB2; MGC126228; MGC126227; RP11-272L14.1; ELF-2; LERK-5; HTK-L; NLERK-1; LERK5; MGC126226; EPL5; EPLG5; EPHRIN-B2
  • Uniprot ID
    P52799
  • Gene Name
    EFNB2; EPLG5; HTKL; LERK5
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human EFNB2 (NP_004084.1) (Met1-Ala229) was expressed with six amino acids (ENLYFQ) at the C-terminus was expressed and purified.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human EFNB2 consists of 209 amino acids and predicts a molecular mass of 23.1 KDa. It migrates as an approximately 32-36 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human Ephrin-B2 / EFNB2 Protein SDS-PAGE

    Human Ephrin-B2 / EFNB2 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"