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Product Name
Human DKK3/REIC/UNQ258/PRO295 (His tag) recombinant protein
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Description
Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine-rich domains that are separated by a 12 amino acid linker region. Dkk-3 also have one prokineticin domain. DKK3 is involved in embryonic development through its inhibition of the WNT signaling pathway. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear.
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Protein name
dickkopf WNT signaling pathway inhibitor 3(DKK3)
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Protein short names
REIC; UNQ258; PRO295
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Uniprot ID
Q9UBP4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human DKK3/REIC/UNQ258/PRO295 Ala22-Ile350 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human DKK3/REIC/UNQ258/PRO295 (His tag) recombinant protein
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