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  • Human DKK3 Recombinant protein (GST tag)

Human DKK3 Recombinant protein (GST tag)

Cat.#: 507248

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human DKK3 Recombinant protein (GST tag)
  • Documents
  • Description
    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
  • Protein name
    Dickkopf-related protein 3
  • Protein short names
    REIC
  • Uniprot ID
    Q9UBP4
  • Gene Name
    DKK3; REIC; UNQ258/PRO295
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    37-350 aa encoded by BC007660 was inserted into PGEX-4T vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human DKK3 SDS-PAGE

    Recombinant human DKK3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"