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  • Human BTN3A1/BTF5 (Fc tag) recombinant protein

Human BTN3A1/BTF5 (Fc tag) recombinant protein

Cat.#: 518867

Special Price 247.5 USD

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Product Information

  • Product Name
    Human BTN3A1/BTF5 (Fc tag) recombinant protein
  • Documents
  • Description
    Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.
  • Protein name
    butyrophilin subfamily 3 member A1(BTN3A1)
  • Protein short names
    BTF5
  • Uniprot ID
    O00481
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human BTN3A1/BTF5 Gln30-Gly254 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human BTN3A1/BTF5 (Fc tag) recombinant protein

    Human BTN3A1/BTF5 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"