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Product Name
Human AOC1/ABP1/DAO1 (His tag) recombinant protein
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Description
Amiloride-sensitive amine oxidase (AOC1) belongs to the copper/topaquinone oxidase family. The protein exists as homodimer by disulfide and mainly located in placenta and kidney. AOC1 catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. The activity of this protein can be inhibited by amiloride in a competitive manner. It is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
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Protein name
amine oxidase, copper containing 1(AOC1)
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Protein short names
ABP1; DAO1
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Uniprot ID
P19801
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human AOC1/ABP1/DAO1 Glu20-Val751 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human AOC1/ABP1/DAO1 (His tag) recombinant protein
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