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  • Human ACVR2A/ACVR2 (Fc & His tag) recombinant protein

Human ACVR2A/ACVR2 (Fc & His tag) recombinant protein

Cat.#: 519831

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Product Information

  • Product Name
    Human ACVR2A/ACVR2 (Fc & His tag) recombinant protein
  • Documents
  • Description
    Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
  • Protein name
    activin A receptor type 2A(ACVR2A)
  • Protein short names
    ACVR2
  • Uniprot ID
    P27037
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ACVR2A/ACVR2 Ala20-Pro134 is expressed with a Fc, 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ACVR2A/ACVR2 (Fc & His tag) recombinant protein

    Human ACVR2A/ACVR2 (Fc & His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"